![]() ![]() The risk of PDPH was 8.10 times more among patients with BMI ≤ 31kg/m 2. Also there was significant association between PDPH and patients of two groups, proportion of PDPH being higher among BMI ≤ 31kg/m 2 group(36.7%) compared to BMI ≥31kg/m 2 group (6.7%). There was significant association between height (P=0.011) and body weight (P≤0.0001) and patients of the two groups. Spinal anaesthesia was administered through midline approach, in postoperative period any incidence of headache and its character noted. Patients body weight and calculated BMI recorded on admission before the procedure. Total 60 patients were divided into two groups, Group A (BMI ≥ 31kg/m 2) and Group B (BMI ≤ 31kg/m 2). We have planned this prospective cohort study to evaluate the relation of body weight with spinal anaesthesia induced headache in parturient mother. Although conflicting results are available in various studies. Body weight or body mass index has been focused as associated to PDPH in recent years. Spinal and unintended dural puncture during epidural procedure is the causal factor, and several risk factors have been attributed to this headache. Post dural puncture headache is a complication of neuraxial anaesthesia. Conclusion: Although there was no significant difference between the parameters studied in the two groups, patients with less age, history of headache, lower CSF pressure, and female gender were more likely to develop PDPH. The mean age of patients with PDPH was significantly lower in both groups, and the percentage of women with PDPH was considerably higher than that of men (P<0.05). Mean severity, onset time, and duration of PDPH were not significantly different between the two groups (P0.05). Results: The incidence of PDPH was lower in the midazolam group, but the difference was not significant (P>0.05). ![]() Patients in both groups were evaluated and compared with each other in terms of incidence, onset, severity, and duration of PDPH. ![]() In the intervention group (n=30), 3 mg of midazolam was injected intravenously for two minutes 5-10 minutes before LP, and the control group received normal saline as placebo. Methods: This single-blind randomized clinical trial study was performed on 120 patients aged 18-60 years who were candidates for diagnostic LP in 2017-2018. The present study aims to evaluate the effect of midazolam on the prevention of PDPH. Objective: Post-dural-puncture headache (PDPH) is the most common side effect associated with a lumbar puncture (LP). ![]()
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